One Pieceis one of the most successful manga and anime in the world, having millions of fans around the world and having reached over one thousand episodes released. Created by Eiichiro Oda, theOne Piecestory follows the beginnings of the Straw Hats through several journeys where they have put it all on the line to come out on top. TheOne Piecefranchise has expanded to multiple different avenues such as animated films, live-action series, and video games; recently released by Bandai Namco Entertainment,One Piece: Odysseyis the newest addition to the franchise string of video games.
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One Piece: Odysseyis an RPG where players will take the Straw Hat Pirates through their most brutal battles in turn-based, team combat. Throughout the game, players will face some of the strongest characters inOne Pieceand have to defeat them to progress further through the game’s story. Here are some of the most challenging Boss battles inOne Piece: Odyssey.
7Hakuba
Hakuba is the dormant personality of Cavendish, a former prince of a faraway kingdom until he was exiled. Cavendish is the captain of the Beautiful Pirate crew but, later on, swore loyalty toMonkey D. Luffyand the Straw Hats after a large battle against Donquixote Doflamingo.
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Hakuba is the darker part of Cavendish which awakens and sends him on a tirade where he cuts down anything in his path. InOne Piece: Odyssey, Hakuba uses powerful dashing strikes that cleave through characters with blinding speed.
6Pica
As one of the top three members of the Donquixote Pirates, Pica stands as a stalwart challenge for players to take on as they make their way through the game. Standing confidently with a massive body of pure muscle, Pica is a near-unstoppable force due to his raw strength and special material power given to him by the Ishi Ishi No Mi devil fruit he ingested.
InOne Piece: Odyssey, Pica utilizes several hard-hitting abilities, including his assimilation ability which forces players to do damage to rock formations in order for Pica to reveal himself and damage his main body.

5Adio Suerte
Adio serves as the final boss ofOne Piece: Odyssey; Adio is the sole survivor of an old race that lived on the sky island, Waford. First Appearing on the cover of chapter 1053 ofOne Piece, little is known about Adio due to his mysterious birth. However, it is known that he was hunted down by the world government for his heritage and knowledge of a devastating weapon. In the game, Adio uses the Divine Breathe, a weapon of unimaginable power, to take on the Straw Hats and exact his revenge on the world.
4Kuzan
Kuzan has also gone by the moniker Aokiji. He was a Marine Admiral before stepping down when Sakazuki was granted a promotion, and he was defeated in a duel. Kuzan left his military life behind and ended up as a member of the Blackbeard Pirates and became one of the main antagonists of the Straw Hat Pirates.
InOne Piece: Odyssey,Kuzan is the fifth boss in the game and utilizes powerful ice techniques thanks to his Hie Hie No Mi; the version of Kuzan that players must fate is while he is still a member of the marines.

3Doflamingo
Doflamingois perhaps the most known villain of theOne Pieceuniverse; serving as the captain of the Donquixote Pirates; once a Warlord of the Sea and King of Dressrosa, Doflomingo lost everything after being defeated by Luffy in theOne Piecemanga; now Dolfamingo resides in prison along with his crew.
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Doflomingo is a hardy boss to get the best of inOne Piece: Odyssey,as he can withstand a large amount of damage, making him very difficult for under-leveled teams. In addition, Doflamingo deals considerable damage with powerful striking attacks and his Ito Ito No Mi ability.
2Crocodile
Crocodile has a long and noteworthy history inOne Piece; he was a former Warlord of the Sea and nearly conquered the entire Arabasta Kingdom.Crocodileis a powerful leader and fierce fighter, having been the first individual to defeat Luffy in combat.
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Crocodile now stands as a supporting character inOne Pieceas a member of the Cross Guild alongside Dracule Mihawk and one of the Four Emperors, Buggy. Crocodile is one of the hardest bosses in One Piece Odyssey with high damage and endurance; Crocodile also uses powerful sand attacks that can hit multiple targets at once.
1Colossus
The Colossi are enemies created specifically for One Piece Odyssey as weapons that guard the Divine Breath. The ancient race that lived on the sky island are responsible for creating the Colossi and the Diving Breath; they are constructs of incredible power and durability that Adio uses to further his goal.
There are several types of Colossus that the player fights against, and each one is a wall of damage absorption and can cast heavy damaging wind attacks. In addition, each Colossus uses a powerful element for damage, such as lightning, wind, fire, and water.



